Cart
sales@molnova.com
Methyltetrazine-PEG5-NHS ester
CAS No. 1802907-92-1
Methyltetrazine-PEG5-NHS ester( —— )
Catalog No. M33430 CAS No. 1802907-92-1
Methyltetrazine-PEG5-NHS ester is a PROTAC linker belonging to the group of PEGs and is used for the synthesis of PROTAC molecules.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 43 | In Stock |
|
| 10MG | 65 | In Stock |
|
| 25MG | 117 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMethyltetrazine-PEG5-NHS ester
-
NoteResearch use only, not for human use.
-
Brief DescriptionMethyltetrazine-PEG5-NHS ester is a PROTAC linker belonging to the group of PEGs and is used for the synthesis of PROTAC molecules.
-
DescriptionMethyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
-
In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
In Vivo——
-
Synonyms——
-
PathwayPROTACs
-
TargetPROTAC
-
RecptorPROTAC Linker
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1802907-92-1
-
Formula Weight533.53
-
Molecular FormulaC24H31N5O9
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(ON1C(=O)CCC1=O)CCOCCOCCOCCOCCOC=2C=CC(=CC2)C3=NN=C(N=N3)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?
molnova catalog
related products
-
MT-802
MT-802 (MT802) is a potent BTK PROTAC that induces degradation of both wild-type and C481S mutant BTK (DC50=9.1 nM).
-
SNIPER(AR)-51
SNIPER(AR)-51 is a specific and nongenetic, protein degradation inducer of androgen receptor, consistiong of AR ligand and IAP ligand and linker; induces proteasomal degradation of AR and shows effective protein knockdown activity.
-
CM11
A homo-PROTAC, bivalent small-molecule dimerizer of the VHL E3 ubiquitin ligase to induce self-degradation; induces potent, rapid and proteasome-dependent self-degradation of VHL in different cell lines.
